Nucleic Acid Vaccines for COVID-19: A Paradigm Shift in the Vaccine Development Arena

Coronavirus disease, COVID-19, has touched every country globally except five countries (North Korea, Turkmenistan, Tonga, Tuvalu and Nauru). Vaccination is the most effective method to protect against infectious diseases. The objective ensure that everyone access a COVID-19 vaccine. conventional vaccine development platforms are complex time-consuming obtain desired approved candidates through rigorous regulatory pathways. These safeguards guarantee optimized product safe efficacious for various demographic populations prior it being general use. Nucleic acid vaccines employ genetic material from pathogen, such as virus or bacteria, induce an immune response it. Based on vaccination, might be DNA RNA; such, offers instructions producing specific pathogen protein system will perceive foreign mount response. multiple antigens made in same facility, lowering costs even more. Most traditional regimens do not allow this. Herein, we demonstrate recent understanding advances nucleic (DNA mRNA based) specifically those human clinical trials.